双(三甲基硅基)氨基钾

• 产品号: L15022
• CAS号: 40949-94-8
• 分子式: C6H18KNSi2
• 分子量: 199.48312
• 纯 度: 15% w/w in toluene

产品别名

• 标题: Potassium bis(trimethylsilyl)amide
• IUPAC标准名: potassium bis(trimethylsilyl)azanide
• IUPAC传统名: potassium bis(trimethylsilyl)azanide
• 别名: Potassium hexamethyldisilazide; KHMDS

产品登记号

• EC号: 424-100-2
• Beilstein号: 4006754
• CAS号: 40949-94-8
• MDL号: MFCD00010330

产品性质

• 纯度: 15% w/w in toluene
• 密度: 0.881
• 闪点: 7°C(44°F)
• 折射率: 1.4900
• GHS危险声明: H225-H314-H318-H361-H373-H336
• 欧盟危险性物质标志: X
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• GHS警示性声明: P210-P280-P301+P310-P305+P351+P338-P315-P402
• 危险公开号: 11-14-34-48/20-63-67
• 安全公开号: 8-16-26-36/37/39-46
• 保存注意事项: Air & Moisture Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 3
• 联合国危险货物编号: UN2924
• 联合国危险货物包装类别(PG): II

参考文献

• Sterically hindered strong base, compare Sodium bis(trimethylsilyl)amide, L13352 and Lithium bis(trimethylsilyl)amide, L15012. Used in the generation of K enolates, preferred to their Li or Na counterparts in some reactions, see e.g.: Tetrahedron Lett., 32, 1779 (1991); J. Am. Chem. Soc., 109, 6881 (1987); 111, 1063 (1989).
• Also used in the Wittig reaction, to give Li salt-free product distribution for selective (Z)-alkene formation: J. Org. Chem., 45, 4260 (1980). Has also been used with 18-crown-6 for selective formation of (Z)-ɑ?-unsaturated esters from phosphonates: Tetrahedron Lett., 24, 4405 (1983).