(-)-Huperzine A

• 产品号: S2251
• CAS号: 102518-79-6
• 分子式: C15H18N2O
• 分子量: 242.31622
• 保 存: -20°C

产品别名

• 标题: (-)-Huperzine A
• IUPAC标准名: (1R,9R)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,10-trien-5-one
• IUPAC传统名: (1R,9R)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,10-trien-5-one

产品登记号

• CAS号: 102518-79-6

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Neurological Disease
Biological Activity:
(-)-Huperzine A is an Acetylcholinesterase inhibitor and NMDA receptor antagonist with an IC50 of 126 μM for NMDA-induced current. Huperzine A, is a naturally occurring sesquiterpene alkaloid compound found in the plant firmoss Huperzia serrata. The IC(50) values of huperzine A were neither altered by changing the concentrations of glycine (2-0.2 μM) and pH (7.4-6.7) in the external solution, nor by addition of Zn(2+) (5 μM) and dithiothreitol (5 mM) to the external solution. [1][2]References on (-)-Huperzine A[1] http://en.wikipedia.org/wiki/Huperzine_A, , [2] Neuroscience., 2001, 105(3):663-9.

参考文献

• Zhang JM et al. Neuroscience. 2001;105(3):663-9.