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Taurine

产品号 S2008 公司名称 Selleck Chemicals
CAS号 107-35-7 公司网站 http://www.selleckchem.com
分子式 C2H7NO3S 电 话 (877) 796-6397
分子量 125.14688 传 真 (832) 582-8590
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保 存 -20°C Chembase数据库ID: 1723

产品价格信息

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产品别名

标题
Taurine
IUPAC标准名
2-aminoethane-1-sulfonic acid
IUPAC传统名
2-aminoethanesulfonic acid
别名
2-Aminoethanesulfonic acid

产品登记号

CAS号 107-35-7

产品性质

成盐信息 Free Base
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area
Description Cardiovascular Disease
Biological Activity
Description Taurine is an organic acid widely distributed in animal tissues.
Targets
IC50
In Vitro Taurine is present in high concentration in algae and in the animals including insects and arthropods, but is generally absent or present in traces in the bacterial and plant kingdoms. [1] In cardiac tissue alone, taurine levels of 20 mM or higher may be found. Taurine availability protects against cholestasis induced by monohydroxy bile acids remains confined to guinea pigs. [2] In addition, Taurine is an essential nutrient for the cat. [3] Oral supplementation of taurine results in increased plasma taurine concentrations and is associated with normalization of left ventricular function in both groups of cats. Myocardial concentrations of taurine are directly related to plasma concentrations and low plasma concentrations are found to be associated with myocardial failure in cats, proposing a direct link occurs between decreased taurine concentration in the myocardium and decreased myocardial mechanical function. [4]
In Vivo
Clinical Trials
Features
References
[1] Huxtable RJ. Prog Neurobiol, 1989, 32(6), 471-533.
[2] Chesney RW. Adv Pediatr, 1985, 32, 1-42.
[3] Knopf K, et al. J Nutr, 1978, 108(5), 773-778.
[4] Pion PD, et al. Science, 1987, 237(4816), 764-768.