氯甲基甲基硫醚

• 产品号: L10858
• CAS号: 2373-51-5
• 分子式: C2H5ClS
• 分子量: 96.5791
• 纯 度: 95%

产品别名

• 标题: Chloromethyl methyl sulfide
• IUPAC标准名: chloro(methylsulfanyl)methane
• IUPAC传统名: chloromethyl methyl sulfide
• 别名: Chlorodimethyl sulfide; Methyl chloromethyl sulfide

产品登记号

• CAS号: 2373-51-5
• MDL号: MFCD00000923
• EC号: 219-148-4
• Beilstein号: 1730851

产品性质

• 纯度: 95%
• 沸点: 104-105°C
• 密度: 1.160
• 闪点: 17°C(62°F)
• 折射率: 1.4980
• GHS危险声明: H225-H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• GHS警示性声明: P210-P241-P303+P361+P353-P305+P351+P338-P405-P501A
• 危险公开号: 11-36/37/38
• RTECS编号: WQ3700000
• 安全公开号: 9-16-26-33-37-60
• 保存注意事项: Moisture Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 3
• 联合国危险货物编号: UN1993
• 联合国危险货物包装类别(PG): II

参考文献

• For reaction with cyclopentadienyl iron dicarbonyl dimer in the formation of an iron-containing methylene transfer agent, see: Org. Synth. Coll., 9, 372 (1998).
• Protects alcohols as their methylthiomethyl (MTM) ethers by reaction, e.g. with NaH/NaI in DME: Tetrahedron Lett., 3269 (1975), or with AgNO₃/Et₃N: Chem. Lett., 1277 (1979). MTM ethers are relatively stable to acid but can be cleaved selectively with HgCl₂ in aqueous acetonitrile or AgNO₃/2,6-lutidine: Tetrahedron Lett., 3269 (1975), by methylation (MeI) and hydrolysis: Austral. J. Chem., 31, 1031 (1978); Chem. Lett., 715 (1984), or with TMS chloride and Ac₂O: Chem. Ind. (London), 223 (1984). For protection of phenols, see: Tetrahedron Lett., 533 (1977); 24, 1189 (1984).
• Can also be used for the preparation of MTM esters of carboxylic acids, e.g. by treatment of the K salt of the acid in the presence of NaI and 18-crown-6: Tetrahedron Lett., 731 (1978) which also describes cleavage with HgCl₂. The ester can also be cleaved with TFA: J. Chem. Soc., Chem. Commun., 224 (1973); or by methylation-hydrolysis: Tetrahedron Lett., 689 (1979).