Research Area: Immunology
Biological Activity:
Azathioprine(Azasan, Imuran) is a drug that suppresses the immune system. Azathioprine is used in organ transplantation and autoimmune disease. Azathioprine is used in organ transplantation and autoimmune disease. Azathioprine interferes with the synthesis of purines (adenine and guanine), which is required for DNA synthesis. Fast-growing cells, including T-cells and B-cells, are particularly affected by the inhibition of purine synthesis. [1] |