Glyburide

• 产品号: S1716
• CAS号: 10238-21-8
• 分子式: C23H28ClN3O5S
• 分子量: 494.00352
• 保 存: -20°C

产品别名

• 标题: Glyburide
• IUPAC标准名: 5-chloro-N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-2-methoxybenzamide
• IUPAC传统名: glibenclamide
• 别名: Glycron; Glynase; Glibenclamide; Micronase

产品登记号

• CAS号: 10238-21-8

产品性质

• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Endocrinology
Biological Activity:
Glyburide (Diabeta)  is an anti-diabetic drug in a class of medications known as sulfonylureas, closely related to sulfa drugs. The drug works by inhibiting ATP-sensitive potassium channels in pancreatic beta cells. This inhibition causes cell membrane depolarization, which causes voltage-dependent calcium channels to open, which causes an increase in intracellular calcium in the beta cell, which stimulates insulin release. [1, 2]

参考文献

• http://en.wikipedia.org/wiki/Glibenclamide