2,2,2-三氯乙基氯甲酯

• 产品号: L06875
• CAS号: 17341-93-4
• 分子式: C3H2Cl4O2
• 分子量: 211.85878
• 纯 度: 97%

产品别名

• 标题: 2,2,2-Trichloroethyl chloroformate
• IUPAC标准名: chloro(2,2,2-trichloroethoxy)methanone
• IUPAC传统名: chloro(2,2,2-trichloroethoxy)methanone
• 别名: 2,2,2-Trichloroethoxycarbonyl chloride; Chloroformic acid 2,2,2-trichloroethyl ester

产品登记号

• MDL号: MFCD00000810
• CAS号: 17341-93-4
• Beilstein号: 970619
• EC号: 241-363-7

产品性质

• 纯度: 97%
• 沸点: 171-172°C
• 密度: 1.539
• 闪点: >100°C(212°F)
• 熔点: 0-2°C
• 折射率: 1.4700
• GHS危险声明: H301-H330-H314-H318
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• GHS警示性声明: P260-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P405-P501A
• 危险公开号: 22-23-34
• 安全公开号: 9-20-26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN3277
• 联合国危险货物包装类别(PG): II

参考文献

• Reagent for the protection of OH groups as their trichloroethyl (Troc) carbonates, specifically cleaved by reduction with zinc: Tetrahedron Lett., 2555 (1967). For a systematic study of the protection of amines as their Troc-carbamates, see: Synthesis, 268 (1981).
• Preferred to ethyl chloroformate for the N-demethylation of tert-amines, since the resulting carbamate can be cleaved by reductive elimination: Tetrahedron Lett., 1325 (1974); Synth. Commun., 7, 79 (1977).
• Effective reagent for dehydration of primary amides to nitriles: Synth. Commun., 30, 3047 (2000).
• For a brief survey of uses of this reagent in synthesis, see: Synlett, 1473 (2007).