Erythromycin

• 产品号: S1635
• CAS号: 114-07-8
• 分子式: C37H67NO13
• 分子量: 733.92678
• 保 存: -20°C

产品别名

• 标题: Erythromycin
• IUPAC标准名: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• IUPAC传统名: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• 别名: Eryc; Ery-Tab; Emgel; Erymax

产品登记号

• CAS号: 114-07-8

产品性质

• 成盐信息: Free Base
• 溶解度: DMSO
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Infection
Biological Activity:
Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma and Legionellosis. [1] In a study of in-vitro and in-vivo susceptibility of Borrelia burgdorferito, erythromycin possessed low activity, having an ED50 of 122.2 (±51.9) mg/kg. [2] For erythromycin, an IC50 of 1.5 μg/ml was observed, indicating a fourfold lower sensitivity of the organisms to this compound. [3]

参考文献

• http://en.wikipedia.org/wiki/Erythromycin