甲氧基乙酰氯

• 产品号: L03210
• CAS号: 38870-89-2
• 分子式: C3H5ClO2
• 分子量: 108.5236
• 纯 度: 97%, stab. with ca 0.3% magnesium oxide

产品别名

• 标题: Methoxyacetyl chloride
• IUPAC标准名: 2-methoxyacetyl chloride
• IUPAC传统名: methoxy-acetyl chloride

产品登记号

• MDL号: MFCD00000728
• CAS号: 38870-89-2
• EC号: 254-169-2
• Beilstein号: 1740244

产品性质

• 纯度: 97%, stab. with ca 0.3% magnesium oxide
• 沸点: 112-113°C
• 密度: 1.185
• 闪点: 28°C(82°F)
• 熔点: <-40°C
• 折射率: 1.4240
• GHS危险声明: H331-H314-H318-H226
• 欧盟危险性物质标志: X
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P280-P305+P351+P338-P309-P310
• 危险公开号: 10-20-34
• 安全公开号: 26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN2920
• 联合国危险货物包装类别(PG): II

参考文献

• Reagent for the chloromethylation of aromatics under Friedel-Crafts conditions, avoiding the use of chloromethyl methyl ether: Tetrahedron Lett., 24, 1933 (1983). For a study of the kinetics of chloromethylation of benzene and toluene in the presence of SnCl₄, see: J. Org. Chem., 62, 2694 (1997). Compare Methoxyacetic acid, B22917.
• Has also been used for the protection of alcohols as methoxyacetate esters, formed in the presence of pyridine, and cleaved using methanolic or aqueous ammonia ca. 20x faster than acetate: Tetrahedron Lett., 4273 (1968). Selective cleavage with Yb(OTf)₃: J. Org. Chem., 61, 4491 (1996), or ethanolamine in IPA: J. Org. Chem., 60, 331 (1995), have also been reported.