Pravadoline(WIN 48098)

• 产品号: S1588
• CAS号: 92623-83-1
• 分子式: C23H26N2O3
• 分子量: 378.46414
• 保 存: -20°C

产品别名

• 标题: Pravadoline(WIN 48098)
• IUPAC标准名: 3-(4-methoxybenzoyl)-2-methyl-1-[2-(morpholin-4-yl)ethyl]-1H-indole
• IUPAC传统名: 3-(4-methoxybenzoyl)-2-methyl-1-[2-(morpholin-4-yl)ethyl]indole
• 别名: WIN 48098

产品登记号

• CAS号: 92623-83-1

产品性质

• 作用靶点: COX
• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Neurological Disease
Biological Activity:
Pravadoline (WIN 48098) is an antiinflammatory and analgesic compound with an IC50 of 4.9 µM for inhibition of the synthesis of prostaglandins (PGs) in mouse brain. Pravadoline (WIN 48098) is related in structure to non-steroidal antinflammtory agents such as indometacin. Pravadoline (WIN 48098) was developed in the 1980s as a new antiinflammatory and prostaglandin synthesis inhibitor, acting through inhibition of the enzyme cyclooxygenase (COX). [1][2]References on Pravadoline (WIN 48098)[1] J Pharmacol Exp Ther., 1990 Nov, 255(2):511-22.[2] http://en.wikipedia.org/wiki/Pravadoline, ,

参考文献

• http://en.wikipedia.org/wiki/Pravadoline