2-乙酰氧基异丁酰氯

• 产品号: L00957
• CAS号: 40635-66-3
• 分子式: C6H9ClO3
• 分子量: 164.58686
• 纯 度: 98%

产品别名

• 标题: 2-Acetoxyisobutyryl chloride
• IUPAC标准名: 1-chloro-2-methyl-1-oxopropan-2-yl acetate
• IUPAC传统名: 1-chloro-2-methyl-1-oxopropan-2-yl acetate
• 别名: 2-Acetoxy-2-methylpropionyl chloride; 1-Chlorocarbonyl-1-methylethyl acetate

产品登记号

• MDL号: MFCD00000708
• CAS号: 40635-66-3
• EC号: 255-016-2
• Beilstein号: 507772

产品性质

• 纯度: 98%
• 沸点: 55-56°C/6mm
• 密度: 1.150
• 闪点: 68°C(154°F)
• 折射率: 1.4290
• GHS危险声明: H314-H318-H335-H227
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P210-P260-P303+P361+P353-P305+P351+P338-P405-P501A
• 危险公开号: 14-34-37
• 安全公开号: 26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3265
• 联合国危险货物包装类别(PG): II

参考文献

• Reagent for conversion of cis-1,2-diols, including nucleosides, via cyclic dioxolanone intermediates, into trans-chloroalkyl acetates. The reaction is selective for the 2'-OH of uridine derivatives and converts pyrimidine nucleosides to their anhydro forms: J. Am. Chem. Soc., 95, 4016 (1973). Application to synthesis of deoxy-sugars, by dechlorination with Bu₃SnH: J. Chem. Soc., Chem. Commun., 677 (1978).
• Reaction of the chloroalkyl acetate (from a cis-glycol) with azide ion provides a route to the cis-amino alcohol: Tetrahedron Lett., 37, 2529 (1996). Compare O-Acetylsalicyloyl chloride, L00919.