氯化硫代甲酸苯酯

• 产品号: L00838
• CAS号: 1005-56-7
• 分子式: C7H5ClOS
• 分子量: 172.632
• 纯 度: 98+%

产品别名

• 标题: Phenyl chlorothionoformate
• IUPAC标准名: phenyl chloromethanethioate
• IUPAC传统名: phenyl chloromethanethioate
• 别名: Phenyl chlorothionocarbonate; Phenyl thionochloroformate

产品登记号

• MDL号: MFCD00004920
• EC号: 213-736-4
• CAS号: 1005-56-7
• Beilstein号: 774830

产品性质

• 纯度: 98+%
• 沸点: 81-83°C/6mm
• 密度: 1.248
• 闪点: 81°C(177°F)
• 折射率: 1.5804
• GHS危险声明: H314-H318-H227
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P280-P305+P351+P338-P309-P310
• 危险公开号: 34
• 安全公开号: 26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3265
• 联合国危险货物包装类别(PG): II

参考文献

• Similarly, amides are dehydrated to nitriles, and formamides to isonitriles under mild conditions: Tetrahedron Lett., 40, 747 (1999).
• Aryl chlorothionoformates react with OH groups to give thiocarbonate esters. These have a much greater tendency to undergo cyclic elimination than their oxygen counterparts, with dehydration as the net result. Thus, e.g. oximes are dehydrated to nitriles under mild conditions: Chem. Commun., 1014 (1970):
  
• Alcohols are converted to alkenes in better yields than in the Chugaev (xanthate pyrolysis) method, succeeding with hindered alcohols which do not readily form xanthates: J. Chem. Soc., Chem. Commun., 1215 (1972); Helv. Chim. Acta, 55, 2277 (1972). Secondary alcohols give thiocarbonate esters which can be reduced to alkanes by tributyltin hydride, in a useful deoxygenation sequence. For use in an enantiospecific synthesis of the antiviral agent ganciclovir phosphonate, see: J. Med. Chem., 37, 1371 (1994).
• Reagent for conversion of imidazoles to imidazole-2-thiones: Synlett, 239 (1995).
• Reagent, alternative to chloroformates, for dealkylation of tertiary amines: Austral. J. Chem., 52, 841 (1999).