溴化乙烯基三苯基膦

• 产品号: L00708
• CAS号: 5044-52-0
• 分子式: C20H18BrP
• 分子量: 369.234681
• 纯 度: 97%

产品别名

• 标题: Vinyltriphenylphosphonium bromide
• IUPAC标准名: ethenyltriphenylphosphanium bromide
• IUPAC传统名: ethenyltriphenylphosphanium bromide
• 别名: Schweizer's Reagent; Triphenylvinylphosphonium bromide

产品登记号

• Beilstein号: 4168860
• MDL号: MFCD00011807
• EC号: 225-740-3
• CAS号: 5044-52-0

产品性质

• 纯度: 97%
• 熔点: 182-186°C
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• 安全公开号: 26-37
• 保存注意事项: Light Sensitive & Hygroscopic
• TSCA收录: 否

参考文献

• Conjugate additions of nucleophiles to the double bond give ?-substituted ethyl triphenylphosphonium salts which can be further reacted by Wittig olefination. Sequential reaction with phthalimide and an aldehyde leads, after hydrazinolysis of the resulting N-allylphthalimide, to 3-substituted allylamines: J. Org. Chem., 46, 3119 (1981). N-Alkyl allylamines can also be prepared from alkylamines: Tetrahedron Lett., 24, 3043 (1983):
  
• A variety of heterocyclic systems can be synthesized by conjugate addition and subsequent Wittig condensation: J. Am. Chem. Soc., 86, 2744, 2963 (1964); J. Org. Chem., 33, 2416 (1968). Use of carbon nucleophiles permits synthesis of carbocyclic systems: J. Org. Chem., 30, 2082 (1965).
• Conjugate addition of organocuprates leads to a new phosphonium salt which can be used in the Wittig olefination. With alkenyl cuprates this provides a stereoselective route to (Z,Z)-1,4-pentadienes: Tetrahedron Lett., 26, 1799 (1985). Sequential reactions, catalyzed by CuBr - Ag₂CO₃ or CuBr - H₂O, with Grignard reagents and Wittig olefination with an aldehyde, have also been reported: J. Org. Chem., 61,9659 (1996):