Sumatriptan succinate

• 产品号: S1432
• CAS号: 103628-48-4
• 分子式: C18H27N3O6S
• 分子量: 413.48848
• 保 存: -20°C

产品别名

• 标题: Sumatriptan succinate
• IUPAC标准名: 1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide; butanedioic acid
• IUPAC传统名: succinic acid; sumatriptan
• 别名: Sumitrex; Imigran; Suminat; mitrex; Imitrex

产品登记号

• CAS号: 103628-48-4

产品性质

• 作用靶点: 5-HT receptor
• 成盐信息: Succinate
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Neurological Disease
Biological Activity:
Sumatriptan succinate(mitrex, Imigran) is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches. Sumatriptan is structurally similar to serotonin (5HT), and is a 5-HT (types 5-HT1D and 5-HT1B) agonist. The specific receptor subtypes it activates are present on the cranial arteries and veins. Acting as an agonist at these receptors, Sumatriptan reduces the vascular inflammation associated with migraine. [1]

参考文献

• http://www.rxlist.com/imitrex-drug.htm