Ketoconazole

• 产品号: S1353
• CAS号: 65277-42-1
• 分子式: C26H28Cl2N4O4
• 分子量: 531.43092
• 保 存: -20°C

产品别名

• 标题: Ketoconazole
• IUPAC标准名: 1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
• IUPAC传统名: (2R,4S)-ketoconazole
• 别名: Kuric; Xolegel; Nizoral; Extina

产品登记号

• CAS号: 65277-42-1

产品性质

• 保存条件: -20°C
• 作用靶点: P450
• 成盐信息: Free Base
• 溶解度: DMSO

产品详细信息

详细说明 (English)

Research Area: Infection
Biological Activity:
Ketoconazole is a synthetic antifungal drug used to prevent and treat skin and fungal infections, especially in immunocompromised patients such as those with AIDS. ketoconazole is structurally similar to imidazole and interferes with the fungal synthesis of ergosterol, a constituent of fungal cell membranes, as well as certain enzymes. [1] 

参考文献

• http://en.wikipedia.org/wiki/Ketoconazole