Genistein

• 产品号: S1342
• CAS号: 446-72-0
• 分子式: C15H10O5
• 分子量: 270.2369
• 保 存: -20°C

产品别名

• 标题: Genistein
• IUPAC标准名: 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
• IUPAC传统名: genistein

产品登记号

• CAS号: 446-72-0

产品性质

• 作用靶点: EGFR EGFR
• 成盐信息: Free Base
• 溶解度: DMSO
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Prostate cancer
Biological Activity:
Genistein is a soy-derived isoflavone and phytoestrogen with antineoplastic activity. Genistein binds to and inhibits protein-tyrosine kinase, thereby disrupting signal transduction and inducing cell differentiation. This agent also inhibits topoisomerase-II, leading to DNA fragmentation and apoptosis, and induces G2/M cell cycle arrest. Genistein exhibits antioxidant, antiangiogenic, and immunosuppressive activities. [1]

参考文献

• http://www.cancer.gov/drugdictionary/?CdrID=43214