Etodolac(Lodine)

• 产品号: S1328
• CAS号: 41340-25-4
• 分子式: C17H21NO3
• 分子量: 287.35354
• 保 存: -20°C

产品别名

• 标题: Etodolac(Lodine)
• IUPAC标准名: 2-[(1R)-1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl]acetic acid
• IUPAC传统名: [(1R)-1,8-diethyl-3H,4H,9H-pyrano[3,4-b]indol-1-yl]acetic acid
• 别名: Lodine XL; Lodine

产品登记号

• CAS号: 41340-25-4

产品性质

• 作用靶点: COX COX
• 成盐信息: Free Base
• 保存条件: -20°C

产品详细信息

详细说明 (English)

Research Area: Inflammation
Biological Activity:
Etodolac (Lodine) is a COX inhibitor with an IC50 of 53.5 nM. Etodolac (Lodine) belongs to a class of compounds called nonsteroidal anti-inflammatory agents (NSAIDs). Etodolac (Lodine) works by reducing the levels of prostaglandins, which are chemicals that are responsible for pain and the fever and tenderness that occur with inflammation. Etodolac (Lodine) blocks the enzyme that makes prostaglandins (cyclooxygenase), resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. [1][2]

参考文献

• http://www.rxlist.com/lodine-drug.htm