您当前所在的位置:首页 > 产品中心 > 产品信息
Adrucil(Fluorouracil)_分子结构_CAS_51-21-8)
点击图片或这里关闭

Adrucil(Fluorouracil)

产品号 S1209 公司名称 Selleck Chemicals
CAS号 51-21-8 公司网站 http://www.selleckchem.com
分子式 C4H3FN2O2 电 话 (877) 796-6397
分子量 130.0772232 传 真 (832) 582-8590
纯 度 电子邮件 sales@selleckchem.com
保 存 -20°C Chembase数据库ID: 426

产品价格信息

请登录

产品别名

标题
Adrucil(Fluorouracil)
IUPAC标准名
5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC传统名
fluorouracil
别名
Fluorouracil
Carac
Efudex
5-FU
Fluoroplex

产品登记号

CAS号 51-21-8

产品性质

作用靶点 Antimetabolites
成盐信息 Free Base
溶解度 DMSO
保存条件 -20°C

产品详细信息

详细说明 (English)
Research Area: Cancer
Biological Activity:
Fluorouracil (5-FU or f5U) is a chemotherapy drug that is a pyrimidine analog which is used in the treatment of cancer. It works through noncompetitive inhibition of thymidylate synthase. Due to its noncompetitive nature and effects on thymidine synthesis, 5-FU is frequently referred to as the "suicide inactivator". It belongs to the family of drugs called antimetabolites. It is typically administered with leucovorin. [1] Fluorouracil IC50 values were observed across the National Cancer Institute NCI60 panel of human tumor cell lines, which exhibit a mean IC50 of 17.6 μM, with a range of 1–501 μM. [2]

参考文献

  • http://en.wikipedia.org/wiki/Fluorouracil