2-氯-4,6-二甲氧基-1,3,5-三嗪

• 产品号: B24474
• CAS号: 3140-73-6
• 分子式: C5H6ClN3O2
• 分子量: 175.57304
• 纯 度: 98%

产品别名

• 标题: 2-Chloro-4,6-dimethoxy-1,3,5-triazine
• IUPAC标准名: 2-chloro-4,6-dimethoxy-1,3,5-triazine
• IUPAC传统名: 2-chloro-4,6-dimethoxy-1,3,5-triazine

产品登记号

• MDL号: MFCD00075607
• EC号: 221-541-0
• CAS号: 3140-73-6
• Beilstein号: 148988

产品性质

• 纯度: 98%
• 沸点: 99-100°C/1mm
• 熔点: 75-79°C
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• 安全公开号: 26-37-60
• TSCA收录: 否

参考文献

• Similarly, carboxylic acids are converted to Weinreb amides by reaction with N,O-dialkyl hydroxylamines: J. Org. Chem., 66, 2534 (2001).
• Reagent for activation of carboxylic acids to nucleophiles: J. Org. Chem., 63, 4248 (1998). Peptide coupling reagent: Synthesis, 917 (1987). With N-methylmorpholine forms the quaternary chloride (DMTMM) which is a valuable low-cost coupling agent in solid-phase peptide synthesis: Synlett, 275 (2000). For a reexamination of the use of the reagent in peptide coupling, see: Tetrahedron Lett., 42, 4161 (2002); see also Appendix 6.
• Can also be used for the esterification of carboxylic acids: Synthesis, 593 (1999). The intermediate active esters can be hydrogenolyzed, providing a simple method for reduction of acids to aldehydes; at higher pressures, further reduction to the alcohol can be effected: J. Org. Chem., 64, 8962 (1999).