3-喹核醇

• 产品号: B21503
• CAS号: 1619-34-7
• 分子式: C7H13NO
• 分子量: 127.18422
• 纯 度: 98+%

产品别名

• 标题: 3-Quinuclidinol
• IUPAC标准名: 1-azabicyclo[2.2.2]octan-3-ol
• IUPAC传统名: 1-azabicyclo 2.2.2 octan-3-ol
• 别名: 1-Azabicyclo[2.2.2]octan-3-ol; 3-Hydroxyquinuclidine

产品登记号

• EC号: 216-578-4
• CAS号: 1619-34-7
• Beilstein号: 104327
• 默克索引号: 148082
• MDL号: MFCD00151326

产品性质

• 纯度: 98+%
• 熔点: 217-224°C
• GHS危险声明: H314-H318
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
• 危险公开号: 34
• RTECS编号: VD6191700
• 安全公开号: 26-36/37/39-45
• 保存注意事项: Air Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3263
• 联合国危险货物包装类别(PG): III

参考文献

• Reagent for selective cleavage of ?-keto esters to ketones in high yield: Synth. Commun., 5, 341 (1975). Geminal diesters are converted to monoesters in high yield under similar conditions: J. Org. Chem., 41, 208 (1976).
• Superior catalyst for the Baylis-Hillman reaction: the addition of acrylic esters to aldehydes, often very slow (4-7 days) with the usual catalyst 1,4-Diazabicyclo[2.2.2]octane, A14003, is much faster (<1 day) in the presence of quinuclidinol: Synth. Commun., 18, 495 (1988); Tetrahedron Lett., 32, 5611 (1991). For more recent discussion and methodology, see: J. Org. Chem., 67, 510 (2002); 68, 692 (2003). For reviews of the Baylis-Hillman reaction, see: Tetrahedron, 44, 4653 (1988); 52, 8001 (1996). The rate of addition of enones to aldehydes is similarly enhanced: Synth. Commun., 18, 495 (1988); 19, 959 (1989).