三异丙基甲硅烷基三氟甲烷磺酸盐

• 产品号: B21127
• CAS号: 80522-42-5
• 分子式: C10H21F3O3SSi
• 分子量: 306.4176496
• 纯 度: 97%

产品别名

• 标题: Triisopropylsilyl trifluoromethanesulfonate
• IUPAC标准名: tris(propan-2-yl)silyl trifluoromethanesulfonate
• IUPAC传统名: triisopropylsilyl trifluoromethanesulfonate
• 别名: Trifluoromethanesulfonic acid triisopropylsilyl ester; TIPS-OTf

产品登记号

• MDL号: MFCD00009913
• CAS号: 80522-42-5
• EC号: 000-000-0
• Beilstein号: 3591541

产品性质

• 纯度: 97%
• 沸点: 45-46°C/0.03mm
• 密度: 1.136
• 闪点: 100°C(212°F)
• 折射率: 1.4150
• GHS危险声明: H314-H318
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
• 危险公开号: 34
• 安全公开号: 26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3265
• 联合国危险货物包装类别(PG): II

参考文献

• Reagent for introduction of the triisopropylsilyl (TIPS) group: Tetrahedron Lett., 22, 3455 (1981); compare Chlorotriisopropylsilane, A17376, and Appendix 4. For general reactions of silyl triflates, see Trimethylsilyl trifluoromethanesulfonate, A12535.
• For use in the synthesis of 2-substituted benzothiopyran-4-ones, see: Synlett, 182 (1996):
  
• A method for protecting both H atoms of a primary amine consists of formation of the succinimide, followed by enolsilylation with TIPS-OTf, to form the 2,5-bis(triisopropylsiloxy)pyrroles. Deprotection can be effected by desilylation with dilute HCl, followed by hydrazinolysis: Tetrahedron Lett., 38, 2617 (1997).
• For a comprehensive review of the TIPS group in organic chemistry, see: Chem. Rev., 95, 1009 (1995).