N,N-二甲基甘氨酸

• 产品号: A19670
• CAS号: 1118-68-9
• 分子式: C4H9NO2
• 分子量: 103.11976
• 纯 度: 98+%

产品别名

• 标题: N,N-Dimethylglycine
• IUPAC标准名: 2-(dimethylamino)acetic acid
• IUPAC传统名: dimethylglycine
• 别名: Dimethylaminoacetic acid

产品登记号

• EC号: 214-267-8
• 默克索引号: 143244
• MDL号: MFCD00004283
• CAS号: 1118-68-9

产品性质

• 纯度: 98+%
• 熔点: 179-183°C
• GHS危险声明: H302
• GHS警示性声明: P264-P270-P301+P312-P330-P501A
• RTECS编号: MB9865000
• 保存注意事项: Hygroscopic
• TSCA收录: 是

参考文献

• Additive which promotes the Heck coupling reaction of unactivated aryl chlorides with alkenes, catalyzed by Pd(II) in the presence of Tetraphenylphosphonium chloride, A10575: Angew. Chem. Int. Ed., 37, 481 (1998). The combination with Bis(benzonitrile)dichloropalladum constitutes a highly active phosphine-free catalyst system for Heck reactions of aryl bromides: Tetrahedron Lett., 39, 8449 (1998); see also: Tetrahedron Lett., 39, 8449 (1998). Promotes the copper(I)-catalyzed Ullmann-type coupling of aryl bromides and iodides with amines: Org. Lett., 5, 2453 (2003), and phenols: Org. Lett., 5, 3799 (2003), to give substituted anilines and diaryl ethers, respectively. Aryl iodides can also be coupled with aliphatic alcohols to give aryl alkyl ethers: Synlett, 243 (2007). In combinatiion with CuI, vinyl halides with phenols give aryl vinyl ethers: Synlett, 1767 (2005).