2,2,2-三溴乙醇

• 产品号: A18706
• CAS号: 75-80-9
• 分子式: C2H3Br3O
• 分子量: 282.75662
• 纯 度: 99%

产品别名

• 标题: 2,2,2-Tribromoethanol
• IUPAC标准名: 2,2,2-tribromoethan-1-ol
• IUPAC传统名: ethanol, 2,2,2-tribromo-
• 别名: 2,2,2-Tribromoethyl alcohol

产品登记号

• EC号: 200-903-1
• CAS号: 75-80-9
• MDL号: MFCD00004671
• Beilstein号: 1733249

产品性质

• 纯度: 99%
• 沸点: 92-93°C/10mm
• 熔点: 77-80°C
• GHS危险声明: H302-H315-H319-H335
• 欧盟危险性物质标志: X
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 22-36/37/38
• RTECS编号: KM3675000
• 安全公开号: 26-36/37
• 保存注意事项: Light Sensitive
• TSCA收录: 是

参考文献

• Carboxyl groups can be protected as tribromoethyl esters, e.g. by reaction of the acid chloride in the presence of N,N-dimethylaniline. The group is readily cleaved with Zn/AcOH: J. Chem. Soc., Pekin 1., 2875 (1993); (cf. 2,2,2-Trichloroethanol, L08163). The group has also been exploited in the activation of carboxylic acids for amidation with amines, by reductive cleavage of the tribromoethyl ester with a P(III) reagent, preferably Hexamethylphosphorous triamide, A12571, and triethylamine. In an analogous esterification method with alcohols, tributylphosphine - DMAP was the preferred system: J. Org. Chem., 64, 1430 (1999).