2-氨基-2-甲基-1-丙醇

• 产品号: A17814
• CAS号: 124-68-5
• 分子式: C4H11NO
• 分子量: 89.13624
• 纯 度: 95%, may cont. ca 5% water

产品别名

• 标题: 2-Amino-2-methyl-1-propanol
• IUPAC标准名: 2-amino-2-methylpropan-1-ol
• IUPAC传统名: 2-amino-2-methyl-1-propanol
• 别名: Isobutanolamine; AMP

产品登记号

• MDL号: MFCD00008051
• EC号: 204-709-8
• 默克索引号: 14449
• CAS号: 124-68-5
• Beilstein号: 505979

产品性质

• 纯度: 95%, may cont. ca 5% water
• 沸点: 164-166°C
• 密度: 0.934
• 闪点: 67°C(152°F)
• 熔点: 24-28°C
• 折射率: 1.4455
• GHS危险声明: H315-H319-H227-H402-H412
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P280G-P273-P305+P351+P338-P337+P313
• 危险公开号: 36/38-52/53
• RTECS编号: UA5950000
• 安全公开号: 61
• TSCA收录: 是

参考文献

• 2-Aryl-4,4-dimethyl-2-oxazolines are activated towards ortho-lithiation: J. Org. Chem., 40, 3058 (1975). Methoxy- or fluoro-substituents in the ortho-position are readily substitutied by organolithiums or Grignards, providing a versatile route to biaryls: J. Am. Chem. Soc ., 97, 7383 (1975). For examples, see: Org. Synth. Coll., 9, 258 (1998). The oxazoline can also be converted to an aldehyde by methylation and borohydride reduction.
  
• Buffer and phosphate acceptor in assay of phosphatases: Methods of Enzymatic Analysis, 3rd ed., H. U. Bergmeyer, Ed., Verlag Chemie, Weinheim (1984), vol. 4, p76.
• For reviews of the use of oxazolines in synthesis, see: Angew. Chem. Int. Ed., 15, 270 (1976); Tetrahedron, 41, 837 (1985); 50, 2297 (1994).
• Precursor of 2-substituted-4,4-dimethyl-2-oxazoline derivatives of carboxylic acids: J. Org. Chem., 39, 2787 (1974), developed by Meyers. The oxazoline, which is readily formed with the acid chloride and thionyl chloride, is stable to base, organometallic reagents, etc., but readily cleaved by dilute acid. For further information on the reactivity of these derivatives, see 2,4,4-Trimethyl-2-oxazoline, L00181.