1H-苯并三唑-1-基氧代三(二甲氨基)磷鎓 六氟磷酸盐

• 产品号: A16140
• CAS号: 56602-33-6
• 分子式: C12H22F6N6OP2
• 分子量: 442.2806212
• 纯 度: 98%

产品别名

• 标题: 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate
• IUPAC标准名: (1H-1,2,3-benzotriazol-1-yloxy)tris(dimethylamino)phosphanium; hexafluoro-λ^5-phosphanuide
• IUPAC传统名: (1,2,3-benzotriazol-1-yloxy)tris(dimethylamino)phosphanium hexafluorophosphate
• 别名: BOP Reagent; Castro's reagent

产品登记号

• CAS号: 56602-33-6
• MDL号: MFCD00011948
• Beilstein号: 4287025
• EC号: 260-279-1

产品性质

• 纯度: 98%
• 熔点: ca 138°C dec.
• GHS危险声明: H228-H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• GHS警示性声明: P210-P241-P305+P351+P338-P302+P352-P405-P501A
• 危险公开号: 11-36/37/38-44
• 安全公开号: 26-37-60
• 保存注意事项: Moisture & Light Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 4.1
• 联合国危险货物编号: UN1325
• 联合国危险货物包装类别(PG): II

参考文献

• Reagent for high yield, low racemization peptide coupling: Tetrahedron Lett., 1219 (1975). See Appendix 6.
• Mild and efficient reagent for the preparation of esters from carboxylic acids and alcohols: Tetrahedron Lett., 36, 4253 (1995); for esterification of amino acids at low temperatures, see: Tetrahedron Lett., 35, 5603 (1994); for use in formation of mixed phosphonate diesters, see: J. Org. Chem., 60, 5214 (1995).
• The carboxyphosphonium salts formed by reaction with carboxylic acids can be reduced with NaBH₄, providng a mild method for reduction of acids to alcohols: Tetrahedron lett., 39, 3319 (1998).
• Promotes the reaction of aliphatic primary amines with CS₂ to give isothiocyanates which can be isolated in high yield or reacted in situ with nucleophiles: J. Chem. Soc., Chem. Commun., 1995 (1995).