4-硝基苄醇

• 产品号: A15742
• CAS号: 619-73-8
• 分子式: C7H7NO3
• 分子量: 153.13538
• 纯 度: 99%

产品别名

• 标题: 4-Nitrobenzyl alcohol
• IUPAC标准名: (4-nitrophenyl)methanol
• IUPAC传统名: 4-nitrobenzyl alcohol

产品登记号

• CAS号: 619-73-8
• Beilstein号: 1424026
• EC号: 210-611-6
• MDL号: MFCD00007376

产品性质

• 纯度: 99%
• 沸点: 185°C/12mm
• 闪点: 180°C(356°F)
• 熔点: 92-95°C
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• RTECS编号: DP0657100
• 安全公开号: 26-37
• TSCA收录: 是

参考文献

• Protection of alcohols as their 4-nitrobenzyl ethers has been carried out, e.g. in the presence of trifluoroacetic anhydride and 2,6-lutidine: Tetrahedron Lett., 31, 389 (1990).
• Selective deprotection at room temperature can be accomplished by sodium dithionite in aqueous acetonitrile: Synth. Commun., 12, 219 (1982). Photolytic cleavage has been employed in the carbohydrate series: J. Org. Chem., 37, 2281, 2285 (1972). For reviews of photoremovable protecting groups, see: Synthesis, 1 (1980); Org. Photochem., 9, 225 (1987). Reduction to the aniline, followed by chemical or electrolytic oxidation has also been reported: Tetrahedron Lett., 31, 389 (1990).
• Has also found use to protect carboxylic acids as their 4-nitrobenzyl esters, particularly in the penicillin and peptide fields. See also 4-Nitrobenzyl bromide, A15236, and 4-Nitrobenzyl chloride, A15749.