五氟苯酚

• 产品号: A15574
• CAS号: 771-61-9
• 分子式: C6HF5O
• 分子量: 184.063556
• 纯 度: 99%

产品别名

• 标题: Pentafluorophenol
• IUPAC标准名: pentafluorophenol
• IUPAC传统名: pentafluorophenol
• 别名: PFP

产品登记号

• CAS号: 771-61-9
• MDL号: MFCD00002156
• Beilstein号: 1912584
• EC号: 212-235-8

产品性质

• 纯度: 99%
• 沸点: 143°C
• 密度: 1.757
• 闪点: 72°C(161°F)
• 熔点: 32-36°C
• 折射率: 1.4270
• GHS危险声明: H301-H311-H314-H318
• 欧盟危险性物质标志: X
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P260-P301+P310-P303+P361+P353-P305+P351+P338-P361-P405-P501A
• 危险公开号: 21/22-34
• RTECS编号: SM6680000
• 安全公开号: 26-36/37/39-45
• TSCA收录: 是
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3261
• 联合国危险货物包装类别(PG): II

参考文献

• Widely used for peptide coupling (see Appendix 6) via the active PFP esters, generally prepared by carbodiimide coupling: Liebigs Ann. Chem., 1421 (1973); Tetrahedron Lett., 1785 (1974). With Fmoc-protected amino acids, the coupling takes place very rapidly, which reduces the amount of Fmoc-cleavage during the peptide bond formation: Synthesis, 325 (1983). Fmoc protected PFP esters have also been applied in solid phase peptide synthesis: Tetrahedron, 44, 843 (1988). PFP esters have been recommended for preparation of derivatives of heterocyclic acids, effective where DCC or DIC alone fail: Synth. Commun., 28, 753 (1998).
• For preparation and use of the moderately stable PFP formate as a formylating agent for amines and amino acids, see: Synthesis, 510 (1987).