氯代乙酸乙酯

• 产品号: A15554
• CAS号: 105-39-5
• 分子式: C4H7ClO2
• 分子量: 122.55018
• 纯 度: 99%

产品别名

• 标题: Ethyl chloroacetate
• IUPAC标准名: ethyl 2-chloroacetate
• IUPAC传统名: ethyl chloroacetate
• 别名: Chloroacetic acid ethyl ester

产品登记号

• 默克索引号: 143783
• MDL号: MFCD00000932
• CAS号: 105-39-5
• EC号: 203-294-0
• Beilstein号: 506455

产品性质

• 纯度: 99%
• 沸点: 142-144°C
• 密度: 1.159
• 闪点: 54°C(149°F)
• 熔点: -26°C
• 折射率: 1.4210
• GHS危险声明: H301-H311-H331-H226-H400
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P210-P301+P310-P303+P361+P353-P361-P405-P501A
• 危险公开号: 23/24/25-50
• RTECS编号: AF9110000
• 安全公开号: 1/2-7/9-45-61
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN1181
• 联合国危险货物包装类别(PG): II

参考文献

• For examples of use in the Darzens reaction with carbonyl compounds to give glycidic esters, see: Org. Synth. Coll., 3, 727 (1955); 4, 459 (1963); reviews: Org. React., 5, 413 (1949); Chem. Rev., 55, 283 (1955). In the presence of base, glycidic esters rearrange to ɑ-substituted aldehydes: Org. Synth. Coll., 3, 733 (1955):
  
• For a theoretical study of a proposed cyclic transition state in the Darzens reaction, see: J. Org. Chem., 61, 6723 (1996).
• Undergoes phase-transfer catalyzed carbene-like addition to activated alkenes to give cyclopropane derivatives: Synth. Commun., 22, 1651 (1992):
  
• Compare (±)-2-Chloropropionic acid, A12860, for a similar reaction.