碘化钠

• 产品号: A15480
• CAS号: 7681-82-5
• 分子式: INa
• 分子量: 149.89424
• 纯 度: 99+% (dry wt., water <1.0%)

产品别名

• 标题: Sodium iodide
• IUPAC标准名: sodium iodide
• IUPAC传统名: sodium iodide

产品登记号

• CAS号: 7681-82-5
• 默克索引号: 148631
• EC号: 231-679-3
• MDL号: MFCD00003532

产品性质

• 纯度: 99+% (dry wt., water <1.0%)
• 沸点: 1300-1304°C
• 密度: 3.67
• 熔点: 651°C
• 折射率: 1.7745
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• RTECS编号: WB6475000
• 安全公开号: 26-37
• 保存注意事项: Hygroscopic
• TSCA收录: 是

参考文献

• Converts alkyl chlorides or bromides to iodides (Finkelstein reaction). Preferred solvents are acetone or MEK, in which NaI, but not the chloride or bromide, is soluble. See, e.g.: Org. Synth. Coll., 2, 476 (1955); 4, 84 (1963). Activated aryl halides, such as 1-chloro-2,4-dinitrobenzene can be converted to iodides by reaction with NaI in DMF: Org. Synth. Coll., 5, 478 (1973).
• Frequently used in catalytic amounts to increase the rate of nucleophilic displacement reactions of alkyl halides and sulfonates; see, for example: Org. Synth. Coll., 9, 46 (1998).
• Ethers can be cleaved to ω-iodo esters with a combination of NaI and an acyl chloride: Tetrahedron Lett., 23, 681 (1982). Cleavage of ethers also occurs in the presence of TMS chloride: Angew. Chem. Int. Ed., 20, 690 (1981); J. Org. Chem., 44, 1247 (1979); 48, 3667 (1983). The same combination also reduces benzylic alcohols to arylmethanes: Tetrahedron Lett., 28, 3817 (1987); Bull. Chem. Soc. Jpn., 62, 3537 (1989) and deprotects MEM ethers: Tetrahedron Lett., 25, 1429 (1984); see 2-Methoxyethoxymethyl chloride, L01050.
• In combination with Titanium(IV) chloride, 14713, reduction of amine oxides and nitrones occurs: Chem. Ber., 123, 647 (1990). Similarly, sulfoxides are reduced to sulfides: Synthesis, 155 (1991), and mild reductive deoximation can be effected: Synth. Commun., 21,1777 (1991).