三光气

• 产品号: A14932
• CAS号: 32315-10-9
• 分子式: C3Cl6O3
• 分子量: 296.7483
• 纯 度: 98%

产品别名

• 标题: Triphosgene
• IUPAC标准名: ditrichloromethyl carbonate
• IUPAC传统名: triphosgene
• 别名: Bis(trichloromethyl) carbonate; BTC

产品登记号

• EC号: 250-986-3
• CAS号: 32315-10-9
• MDL号: MFCD00062848
• Beilstein号: 1787583

产品性质

• 纯度: 98%
• 沸点: 203-206°C
• 密度: 1.600
• 熔点: 77-91°C
• GHS危险声明: H330-H314-H318
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• GHS警示性声明: P260-P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501A
• 危险公开号: 23-29-34
• 安全公开号: 4-7/8-9-20-26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN2928
• 联合国危险货物包装类别(PG): II

参考文献

• Convenient crystalline alternative to phosgene in many reactions. See also Trichloromethyl chloroformate, A17444. Possible applications include conversion of amines to isocyanates, diols to carbonates, acids to acyl halides, etc.: Angew. Chem. Int. Ed., 26, 894 (1987). For a brief review, see: J. Prakt. Chem./ Chem. Ztg., 337, 516 (1995); for a comprehensive review: Synthesis, 553 (1996).
• In combination with triphenylphosphine, is a mild reagent for the conversions of alcohols to alkyl chlorides: Synth. Commun., 23, 711 (1993), epoxides to vicinal dichlorides: Synth. Commun., 24, 1715 (1994), and acids to acyl chlorides: Tetrahedron Lett., 38, 6489 (1997).
• Trap for titanocycle intermediates in the bicyclization of enynes using the titanocene dichloride (Bis(cyclopentadienyl)titanium dichloride, A11456) - Mg metal system: J. Org. Chem., 63, 9285 (1998):
  
• In combination with triethylamine, dehydrates formamides to isocyanides, and carboxylic acids to their anhydrides: J. Org. Chem., 58, 1646 (1993); 59, 2913 (1994).
• In combination with Dimethyl sulfoxide, A13280, has been used for the low-temperature Swern-type oxidation of alcohols to aldehydes: J. Org. Chem., 56, 5948 (1991); 58, 1646 (1993); Org. Prep. Proced. Int., 24, 363 (1992). Compare Oxalyl chloride, A18012.