三甲基N氧化二水合物

• 产品号: A14916
• CAS号: 62637-93-8
• 分子式: C3H13NO3
• 分子量: 111.14022
• 纯 度: 98+%

产品别名

• 标题: Trimethylamine N-oxide dihydrate
• IUPAC标准名: N,N-dimethylmethanamine oxide dihydrate
• IUPAC传统名: trimethylamine-n-oxide dihydrate

产品登记号

• 默克索引号: 149710
• MDL号: MFCD00149077
• Beilstein号: 3612927
• CAS号: 62637-93-8

产品性质

• 纯度: 98+%
• 熔点: 96-101°C
• GHS危险声明: H315-H319
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P280-P305+P351+P338-P302+P352-P321-P362-P332+P313
• 危险公开号: 36/38
• RTECS编号: YH2850000
• 安全公开号: 26-37
• TSCA收录: 是

参考文献

• For use as a reoxidant in the catalytic cis-hydroxylation of alkenes with Osmium(VIII) oxide, 12103, see: Tetrahedron Lett., 21, 449 (1980).
• Deprotonation by LDA at low temperature gives the unstable azomethine ylide, which undergoes 1,3-dipolar addition, even with unactivated alkenes, to give pyrrolidines: J. Chem. Soc., Chem. Commun., 31 (1983):
  
• Reagent for the liberation of organics from their complexes with iron carbonyls. Partial oxidation of CO to CO₂ takes place: J. Chem. Soc., Chem. Commun., 336 (1974).
• Also oxidizes alkylboranes to alcohols, giving less interference with other functionality than the more usual H₂O₂: J. Org. Chem., 40, 1776 (1975).
• Has been used in the oxidation of alkyl halides to aldehydes. For a procedure, including dehydration of the N-oxide by distillation of water with DMF, see: Org. Synth. Coll., 5, 872 (1973):
  
• For an improved procedure using DMSO, see: Tetrahedron Lett., 31, 4825 (1990).
• Reviews: Trimethylamine as a useful oxidizing agent: J. Prakt. Chem./ Chem. Ztg., 338, 190 (1996); The utility of N-oxides in synthesis: Synthesis, 263 (1993).
• Compare also 4-Methylmorpholine N-oxide monohydrate, A15996.