苯甲硫醚

• 产品号: A14846
• CAS号: 100-68-5
• 分子式: C7H8S
• 分子量: 124.20342
• 纯 度: 99%

产品别名

• 标题: Thioanisole
• IUPAC标准名: (methylsulfanyl)benzene
• IUPAC传统名: thioanisole
• 别名: Methyl phenyl sulfide

产品登记号

• Beilstein号: 1904179
• CAS号: 100-68-5
• MDL号: MFCD00008559
• EC号: 202-878-2

产品性质

• 纯度: 99%
• 沸点: 188-189°C
• 密度: 1.058
• 闪点: 57°C(135°F)
• 熔点: -15°C
• 折射率: 1.5860
• GHS危险声明: H226-H302-H315-H319-H335
• 欧盟危险性物质标志: X
• GHS警示性声明: P261-P280F
• 危险公开号: 22-36/37/38
• RTECS编号: DA6200000
• 安全公开号: 26-36/37
• TSCA收录: 是
• 联合国危险货物等级: 3
• 联合国危险货物编号: UN1993
• 联合国危险货物包装类别(PG): III

参考文献

• Monolithiation is thought to occur initially on the ring, but rearrangement then gives the more stable phenylthiomethyllithium: J. Org. Chem., 31, 4097 (1966); Tetrahedron Lett., 1961 (1977). Further metallation occurs at the ortho-position. See, e.g.: Tetrahedron, 46, 861 (1990). Demetallation and acylation is the basis of a route to 3-substituted benzo[b]thiophenes: Synthesis, 888 (1988):
  
• Cation scavenger in the acidic deprotection of peptides; see, e.g.: Int. J. Pept. Prot. Res., 36, 255 (1990). See Appendix 6. The combination of the soft nucleophile thioanisole and the hard acid triflic acid has been used for the cleavage of methyl ethers, e.g. O-methyltyrosine, resistant to other methods: J. Chem. Soc., Chem. Commun., 971 (1979). The same conditions have been used for the cleavage of Cbz, Boc, benzyl and 4-methoxybenzyl protecting groups in peptide synthesis: Chem. Pharm. Bull., 28, 1214 (1980); 29, 600 (1981); J. Chem. Soc., Chem. Commun., 101 (1980); see also: Angew. Chem. Int. Ed., 33, 1729 (1994).