您当前所在的位置:首页 > 产品中心 > 产品信息
2-溴噻唑_分子结构_CAS_3034-53-5)
点击图片或这里关闭

2-溴噻唑

产品号 A14838 公司名称 Alfa Aesar
CAS号 3034-53-5 公司网站 http://www.alfa.com
分子式 C3H2BrNS 电 话
分子量 164.02368 传 真
纯 度 99% 电子邮件
保 存 Chembase数据库ID: 21406

产品价格信息

请登录

产品别名

标题
2-Bromothiazole
IUPAC标准名
2-bromo-1,3-thiazole
IUPAC传统名
thiazole, 2-bromo-

产品登记号

EC号 221-229-4
MDL号 MFCD00005316
Beilstein号 105724
CAS号 3034-53-5

产品性质

纯度 99%
沸点 171°C
密度 1.836
闪点 63°C(145°F)
折射率 1.5930
GHS危险品标识 GHS07
GHS危险声明 H315-H319-H335-H227
欧盟危险性物质标志 刺激性(Irritant) 刺激性(Irritant) (Xi)
GHS警示性声明 P210-P305+P351+P338-P302+P352-P321-P405-P501A
危险公开号 36/37/38
安全公开号 26-37
TSCA收录

产品详细信息

参考文献

  • 2-Lithiothiazole can be obtained by direct lithiation of thiazole or, more conveniently, by exchange with 2-bromothiazole using n-BuLi: J. Org. Chem., 53, 1748 (1988). It behaves as a valuable formyl anion equivalent, and as such has been applied, mainly by Dondoni's group, in the syntheses of a variety of products; see, e.g.: Tetrahedron Lett., 34, 7319, 7323, 7327 (1993). See also 2-(Trimethylsilyl)thiazole, B21903. Reaction of 2-lithiothiazole with nitrones gives ɑ-aminoaldehydes: Tetrahedron Lett., 33, 4221 (1992); stereocontrolled addition to C-galacto-pyranosylnitrone has been used in syntheses of destomic acid, a component of the antibiotics destomycin and hygromycin, and of lincosamine, the sugar component of the anticancer antibiotic lincomycin: Synlett, 78 (1993). For applications of 2-lithiothiazole in the synthesis of the aza-sugar (+)-galactostsin, see: J. Org. Chem., 60, 4749 (1995). The Thiazole Aldehyde Synthesis has been reviewed by Dondoni: Synthesis, 1681 (1998).