1,1'-羰基二咪唑

• 产品号: A14688
• CAS号: 530-62-1
• 分子式: C7H6N4O
• 分子量: 162.14874
• 纯 度: 97%

产品别名

• 标题: 1,1'-Carbonyldiimidazole
• IUPAC标准名: 1-(1H-imidazole-1-carbonyl)-1H-imidazole
• IUPAC传统名: carbonyldiimidazole
• 别名: CDI

产品登记号

• EC号: 208-488-9
• CAS号: 530-62-1
• 默克索引号: 141819
• MDL号: MFCD00005286
• Beilstein号: 6826

产品性质

• 纯度: 97%
• 熔点: 116-120°C
• GHS危险声明: H301-H314-H318
• 欧盟危险性物质标志: X
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P260-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501A
• 危险公开号: 22-34
• 安全公开号: 26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3263
• 联合国危险货物包装类别(PG): II

参考文献

• Reagent for peptide coupling via the acylimidazolide: Liebigs Ann. Chem., 609, 75 (1957); J. Am. Chem. Soc., 80, 4423 (1958); 82, 4596 (1960): J. Org. Chem., 27, 2094 (1962). For peptide reagents, see Appendix 6.
• One-pot esterification of a carboxylic acid with t-BuOH occurs in the presence of DBU: Synthesis, 833 (1982). The reactivity of acyl imidazolides can be increased by N-alkylation: Chem. Pharm. Bull., 32, 5044 (1984).
• Acylimidazolides can also be reduced to aldehydes by DIBAL-H. This reaction has been applied to N-protected amino acids: J. Chem. Soc., Chem. Commun., 79 (1979).
• Dehydrates aldoximes, including chiral oximes, to nitriles in high yield: J. Chem. Soc., Chem. Commun., 628 (1973); Synth. Commun., 12, 25 (1982). Ketoximes can be converted to amides by the spontaneous Beckmann rearrangement of imidazolium salts: Chem. Pharm. Bull., 32, 2560 (1984):
  
• ?-Hydroxy amino acids are dehydrated to dehydroamino acids: Synthesis, 968 (1982).
• ɑ?-Dihydroxyketones are converted toɑ-diketones: Synth. Commun., 23, 2219 (1993).