(甲氧基羰基亚甲基)三苯基膦烷

• 产品号: A14020
• CAS号: 2605-67-6
• 分子式: C21H19O2P
• 分子量: 334.348121
• 纯 度: 98%

产品别名

• 标题: (Methoxycarbonylmethylene)triphenylphosphorane
• IUPAC标准名: methyl 2-(triphenyl-λ^5-phosphanylidene)acetate
• IUPAC传统名: methyl 2-(triphenyl-λ^5-phosphanylidene)acetate
• 别名: (Carbomethoxymethylene)triphenylphosphorane; Methyl (triphenylphosphoranylidene)acetate

产品登记号

• MDL号: MFCD00008455
• Beilstein号: 618430
• EC号: 220-018-4
• CAS号: 2605-67-6

产品性质

• 纯度: 98%
• 熔点: 165-169°C
• 保存注意事项: Air Sensitive
• TSCA收录: 是

参考文献

• For tandem Wittig reaction and Cope rearrangement, see: J. Chem. Soc., Chem. Commun., 381 (1995):
  
• Review of phosphacumulene ylides: Angew. Chem. Int. Ed.,16, 349 (1977).
• Stable ylide which undergoes the Wittig reaction with aldehydes to give substituted methyl acrylates. See also (Ethoxycarbonylmethylene)triphenylphosphorane, A12896 and Appendix 1. For a detailed study of the reaction with benzaldehyde, see J. Org. Chem., 59, 1126 (1994). For use of high pressure to increase the yield and trans-selectivity of reaction with aromatic aldehydes, see: Liebigs Ann. Chem., 2135 (1983).
• Strong base, for example Na bis(TMS)amide, brings about elimination of methanol, giving ketenylidenetriphenylphosphorane, which reacts with ɑ-hydroxy-ketones, e.g. in the steroid series, to give butenolides, by acylation and Wittig cyclization: Chem. Ber., 113, 2038 (1980):