磷酸乙酸三甲酯

• 产品号: A13301
• CAS号: 5927-18-4
• 分子式: C5H11O5P
• 分子量: 182.111601
• 纯 度: 98%

产品别名

• 标题: Trimethyl phosphonoacetate
• IUPAC标准名: methyl 2-(dimethoxyphosphoryl)acetate
• IUPAC传统名: methyl 2-(dimethoxyphosphoryl)acetate
• 别名: Phosphonoacetic acid trimethyl ester; Dimethyl methoxycarbonylmethylphosphonate

产品登记号

• EC号: 227-663-0
• Beilstein号: 1865177
• MDL号: MFCD00008452
• CAS号: 5927-18-4

产品性质

• 纯度: 98%
• 沸点: 119-120°C/1mm
• 密度: 1.263
• 闪点: 70°C(158°F)
• 折射率: 1.4370
• GHS危险声明: H315-H319-H335-H227
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P210-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• 安全公开号: 9-36
• TSCA收录: 是

参考文献

• Horner-Wadsworth-Emmons olefination (see Appendix 1) with aldehydes and ketones gives acrylic esters, cf Triethyl phosphonoacetate, A14120. In general, the (E):(Z) ratio of the resulting alkene increases as the counter-ion becomes smaller (K, Na, Li) and as the temperature increases. See, e.g.: J. Org. Chem., 55, 3386 (1990). Reaction with ɑ-hydroxy ketones provides a simple route to butenolides: Tetrahedron Lett., 36, 2839 (1995):