环己烯氧化物

• 产品号: A13185
• CAS号: 286-20-4
• 分子式: C6H10O
• 分子量: 98.143
• 纯 度: 98+%

产品别名

• 标题: Cyclohexene oxide
• IUPAC标准名: 7-oxabicyclo[4.1.0]heptane
• IUPAC传统名: 7-oxabicyclo 4.1.0 heptane
• 别名: 7-Oxabicyclo[4.1.0]heptane; Epoxycyclohexane

产品登记号

• EC号: 206-007-7
• Beilstein号: 383568
• CAS号: 286-20-4
• MDL号: MFCD00005162

产品性质

• 纯度: 98+%
• 沸点: 129-130°C
• 密度: 0.972
• 闪点: 24°C(75°F)
• 熔点: -40°C
• 折射率: 1.4520
• 溶解度: Insoluble in water
• GHS危险声明: H311-H302-H332-H314-H318-H226
• 欧盟危险性物质标志: X
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P210-P303+P361+P353-P305+P351+P338-P361-P405-P501A
• 危险公开号: 10-20/21/22-34
• RTECS编号: RN7175000
• 安全公开号: 9-26-36/37/39-45-60
• TSCA收录: 是
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN2920
• 联合国危险货物包装类别(PG): II

参考文献

• A general method for the conversion of epoxides to cis-dichloro alkanes, with inversion at both centers, by reaction with triphenylphosphine dichloride, has been exemplified: Org. Synth. Coll., 6, 424 (1988).
• Rearrangement to cyclopentanecarboxaldehyde is catalyzed by LiBr on alumina, either by refluxing in toluene or in the gas phase: Synthesis, 394 (1988). An alternative isomerization to the allylic alcohol is induced by base catalysis. Optimized conditions use a mixture of KO-t-Bu and 2.5 equivalents of LDA: Tetrahedron, 46, 2411 (1990). For discussion of the mechanism, see: J. Org. Chem., 61, 820 (1996), and references therein. For a review of the rearrangement of epoxides to allylic alcohols, see: Org. React., 29, 345 (1983).
• A general method for the synthesis of ɑ-chloro carbonyl compounds is illustrated by the reaction of cylohexene oxide with the Swern reagent (DMSO/oxalyl chloride) to give 2-chlorocyclohexanone in 93% yield: Tetrahedron, 51, 2467 (1995).