二苯基甲醇

• 产品号: A12884
• CAS号: 91-01-0
• 分子式: C13H12O
• 分子量: 184.23378
• 纯 度: 99%

产品别名

• 标题: Benzhydrol
• IUPAC标准名: diphenylmethanol
• IUPAC传统名: benzhydrol
• 别名: Diphenylcarbinol; Diphenylmethanol

产品登记号

• Beilstein号: 1424379
• CAS号: 91-01-0
• EC号: 202-033-8
• MDL号: MFCD00004488
• 默克索引号: 141090

产品性质

• 纯度: 99%
• 沸点: 297-298°C
• 闪点: 160°C(320°F)
• 熔点: 64-68°C
• GHS危险声明: H303-H402-H412
• GHS警示性声明: P273-P312-P501A
• 危险公开号: 52/53
• RTECS编号: DC7452000
• 安全公开号: 61
• TSCA收录: 是

参考文献

• The protection of OH groups as benzhydryl ethers can be catalyzed by sulfuric acid: Org. Synth. Coll., 4, 72 (1963); Angew. Chem. Int. Ed., 15, 281 (1976). See also Benzhydryl bromide, L02211. Thiols, e.g. in cysteine residues in peptide synthesis, can be protected as thioethers in the presence of TFA or HBr/AcOH: J. Chem. Soc. (C), 2683 (1970). The group can be cleaved by TFA in the presence of a cation scavenger, e.g. phenol or anisole (same ref.), or by Na in liquid NH₃: J. Am. Chem. Soc., 84, 3887 (1962). See Appendix 6.
• Carboxyl groups can be protected by esterification in benzene with tosic acid catalyst. Deprotection can be effected with the same catalyst by refluxing in toluene, which undergoes electrophilic alkylation: Tetrahedron Lett., 37, 1965 (1996).