硫脲

• 产品号: A12828
• CAS号: 62-56-6
• 分子式: CH4N2S
• 分子量: 76.12086
• 纯 度: 99%

产品别名

• 标题: Thiourea
• IUPAC标准名: thiourea
• IUPAC传统名: thion
• 别名: Thiocarbamide

产品登记号

• CAS号: 62-56-6
• Beilstein号: 605327
• MDL号: MFCD00008067
• EC号: 200-543-5
• 默克索引号: 149367

产品性质

• 危险公开号: 22-40-51/53-63
• RTECS编号: YU2800000
• 安全公开号: 36/37-61
• TSCA收录: 是
• 联合国危险货物等级: 9
• 联合国危险货物编号: UN3077
• 联合国危险货物包装类别(PG): III
• GHS危险声明: H351-H361-H302-H411-H401
• 欧盟危险性物质标志: X
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P280H-P273
• 纯度: 99%
• 密度: 1.405
• 熔点: 172-178°C

参考文献

• Reagent for the conversion of alkyl halides to thiols by base hydrolysis of the isothiouronium salts; see also N-Acetylthiourea, B21198. Cleavage of isothiouronium salts with base and alkylation of the resulting thiolate has been used as a convenient synthesis of unsymmetrical sulfides: Synth. Commun., 14, 209 (1984).
• Epoxides are converted to episulfides: J. Org. Chem., 26, 3467 (1961). The 2,3-epoxy alcohols resulting from the Sharpless enantioselective epoxidation can be converted to the corresponding episulfides with retention at both centers, using Ti(O-i-Pr)₄ as mediator: J. Org. Chem., 53, 4114 (1988).
• Widely used in heterocyclic syntheses, e.g. of thiazoles and pyrimidines.
• Has been used in a convenient synthesis of isothiocyanates from oximes via the nitrile oxide: Tetrahedron Lett., 34, 8283 (1993); see also Benzaldoxime, A12053: