2-氯-1-甲基碘化吡啶鎓

• 产品号: A12820
• CAS号: 14338-32-0
• 分子式: C6H7ClIN
• 分子量: 255.48395
• 纯 度: 97%

产品别名

• 标题: 2-Chloro-1-methylpyridinium iodide
• IUPAC标准名: 2-chloro-1-methylpyridin-1-ium iodide
• IUPAC传统名: 2-chloro-1-methylpyridin-1-ium iodide
• 别名: N-Methyl-2-chloropyridinium iodide; Mukaiyama's Reagent

产品登记号

• Beilstein号: 3572320
• 默克索引号: 146301
• CAS号: 14338-32-0
• EC号: 238-288-7
• MDL号: MFCD00011984

产品性质

• 纯度: 97%
• 熔点: ca 200°C dec.
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• 安全公开号: 26-37
• 保存注意事项: Moisture & Light Sensitive
• TSCA收录: 否

参考文献

• Carboxylic acids are coupled with nucleophiles, YH, according to the following scheme:
  
• Applications include:
• Useful reagent in a wide variety of dehydrative coupling reactions. For a review of the chemistry of this and related reagents, see: Angew. Chem. Int. Ed., 18, 707 (1979). For peptide reagents, see Appendix 6.
• Synthesis of esters: Chem. Lett., 1163 (1975); Bull. Chem. Soc. Jpn., 50, 1863 (1977); macrolides: Chem. Lett., 49 (1976); Tetrahedron Lett., 30, 3209 (1989); and strained, trans-fused -lactones: Synthesis, 493 (1983). Formation of?-lactams from ?-amino acids: Synthesis, 210 (1979); Chem. Lett., 1465 (1984), or from carboxylic acids and imines: Tetrahedron Lett., 32, 581 (1991); cyclization of a macrocyclic amide: J Am. Chem. Soc., 111, 1157 (1989). Coupling of carboxylic acids with N,O-dimethylhydroxylamine gives the Weinreb amide: Synth. Commun., 25, 1255 (1995).
• Conversion of thioureas to carbodiimides: Chem. Lett., 575 (1977); in the presence of a primary amine the guanidine is formed: J. Org. Chem., 62, 1540 (1997). Generation of ketenes from carboxylic acids: Synlett, 36 (1989).