肼基甲酸叔丁酯

• 产品号: A12383
• CAS号: 870-46-2
• 分子式: C5H12N2O2
• 分子量: 132.16098
• 纯 度: 98+%

产品别名

• 标题: tert-Butyl carbazate
• IUPAC标准名: (tert-butoxy)carbohydrazide
• IUPAC传统名: tert-butoxycarbohydrazide
• 别名: Boc-hydrazine; tert-Butoxycarbonylhydrazine

产品登记号

• Beilstein号: 1756967
• CAS号: 870-46-2
• MDL号: MFCD00007593
• EC号: 212-795-3

产品性质

• 纯度: 98+%
• 沸点: 63-65°C/0.1mm
• 闪点: 91°C(195°F)
• 熔点: 37-41°C
• GHS危险声明: H228
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• GHS警示性声明: P210-P241-P280-P240-P370+P378A
• 危险公开号: 11
• 安全公开号: 33
• 保存注意事项: Moisture Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 4.1
• 联合国危险货物编号: UN1325
• 联合国危险货物包装类别(PG): III

参考文献

• Monoalkylhydrazines can be prepared via reduction of Boc-hydrazones with borane-THF, and cleavage with HCl: J. Org. Chem., 46, 5413 (1981).
• Protected hydrazine derivative, permitting selective reaction at one N atom, followed by mild acidic cleavage of the Boc group. For preparation of, e.g. N-aminosuccinimide, free from the cyclic hydrazide, see: J. Org. Chem., 37, 2040 (1972). Similarly, reaction with carbonyl or sulfonyl halides, followed by cleavage with HCl, provides a route to monoacyl hydrazides: Synthesis, 244 (1980). It is also commonly used in the synthesis of aza-amino acids; see, for example: Synthesis, 141 (1991) and references therein.
• Precursor of the somewhat unstable tert-butyl azidoformate, useful for introduction of the Boc protecting group, see: Org. Synth. Coll., 5, 157 (1973). Caution! Possible violent decomposition of this azide on heating.