吡啶

• 产品号: A12005
• CAS号: 110-86-1
• 分子式: C5H5N
• 分子量: 79.0999
• 纯 度: 99+%

产品别名

• 标题: Pyridine
• IUPAC标准名: pyridine
• IUPAC传统名: pyridine

产品登记号

• MDL号: MFCD00011732
• Beilstein号: 103233
• CAS号: 110-86-1
• EC号: 203-809-9
• 默克索引号: 147970

产品性质

• 纯度: 99+%
• 沸点: 115°C
• 密度: 0.978
• 闪点: 20°C(68°F)
• 熔点: -42°C
• 折射率: 1.5100
• 溶解度: Miscible with water, alcohol, ether, pet ether, oils
• GHS危险声明: H225-H311-H302-H332
• 欧盟危险性物质标志: X
• 欧盟危险性物质标志: 易燃性(Flammable) (F)
• GHS警示性声明: P210-P241-P303+P361+P353-P361-P405-P501A
• 危险公开号: 11-20/21/22
• RTECS编号: UR8400000
• 安全公开号: 26-28
• TSCA收录: 是
• 联合国危险货物等级: 3
• 联合国危险货物编号: UN1282
• 联合国危险货物包装类别(PG): II

参考文献

• Widely used as a base and nucleophilic catalyst in acylations, sulfonylations, etc. See also 4-(Dimethylamino)pyridine, A13016.
• Reacts with thionyl chloride to give N-(4-pyridyl)pyridinium chloride hydrochloride, a useful intermediate for the preparation of 4-substituted pyridines by nucleophilic displacement. Thus, reaction with sulfite ion gives the sulfonate: Org. Synth. Coll., 5, 977 (1973). Similarly, pyridine can be activated tosubstitution at the 4-position by reaction with Ethyl chloroformate, L06311, or tert-Butyldimethylsilyl trifluoromethanesulfonate, A12174. The acyl or silyl pyridinium salt then reacts with Grignards or organocuprates, to give 4-substituted dihydropyridines which can readily be rearomatized: Bull. Chem. Soc. Jpn., 57, 1994 (1984).
• For use in Cr(VI) oxidation reactions, see Chromium(VI) oxide, 12522.