2-溴噻吩

• 产品号: A11959
• CAS号: 1003-09-4
• 分子式: C4H3BrS
• 分子量: 163.03562
• 纯 度: 98+%

产品别名

• 标题: 2-Bromothiophene
• IUPAC标准名: 2-bromothiophene
• IUPAC传统名: 2-bromothiophene
• 别名: 2-Thienyl bromide

产品登记号

• CAS号: 1003-09-4
• Beilstein号: 104663
• MDL号: MFCD00005417
• EC号: 213-699-4

产品性质

• 纯度: 98+%
• 沸点: 149-152°C
• 密度: 1.701
• 闪点: 58°C(136°F)
• 熔点: <-10°C
• 折射率: 1.5860
• GHS危险声明: H300-H310-H330-H315-H319-H226
• 欧盟危险性物质标志: 有毒(Toxic) (T)
• GHS警示性声明: P210-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P361-P405-P501A
• 危险公开号: 23/24/25-36/38
• 安全公开号: 9-26-27-36/37/39-45-60
• 保存注意事项: Light Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN2929
• 联合国危险货物包装类别(PG): II

参考文献

• The bromo-substituent can be readily displaced by methoxide in methanol in the presence of a Cu(I) catalyst: Synth. Commun., 20, 213 (1990). For coupling reaction with Thiophene-2-thiol, B22642, in the presence of Cu₂O, to give 2,2'-dithienyl sulfide, see: Org. Synth. Coll., 6, 558 (1988).
• Allylic alcohols are thienylated by means of a Heck-type, Pd-catalyzed coupling reaction; the products are ketones formed by rearrangement: Chem. Lett., 423 (1977). Coupling with iodoarenes can be induced at the 5-position by the use of a palladium(II) catalyst in the presence of silver nitrate and potassium fluoride, providing access to 5-aryl-2-bromothiophene derivatives, which may be further elaborated by reaction with the available 2-bromo-substituent: Org. Lett., 7, 5083 (2005).