三苯基氯甲烷

• 产品号: A11799
• CAS号: 76-83-5
• 分子式: C19H15Cl
• 分子量: 278.7754
• 纯 度: 98%

产品别名

• 标题: Chlorotriphenylmethane
• IUPAC标准名: (chlorodiphenylmethyl)benzene
• IUPAC传统名: triphenylmethyl chloride
• 别名: Trityl chloride; Triphenylmethyl chloride

产品登记号

• CAS号: 76-83-5
• EC号: 200-986-4
• MDL号: MFCD00000813
• Beilstein号: 397363

产品性质

• 纯度: 98%
• 沸点: 230-235°C/20mm
• 熔点: 110-114°C
• GHS危险声明: H314-H318-H400-H410
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P280-P273-P305+P351+P338-P309-P310
• 危险公开号: 34-50/53
• RTECS编号: PA6450000
• 安全公开号: 26-36/37/39-45-60-61
• 保存注意事项: Moisture Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3261
• 联合国危险货物包装类别(PG): II

参考文献

• Reagent for protection of N, S and particularly O functions as trityl (Trt) derivatives, stable to a wide range of conditions, but readily cleaved by mild acid.
• For an improved method for O-tritylation in triethylamine in the presence of catalytic amounts of DMAP, see: Tetrahedron Lett., 95 (1979).
• Progressively more acid-labile protecting groups contain one, two or three p-methoxy-groups: 4-Methoxytrityl chloride, A10545, 4,4'-Dimethoxytrityl chloride, A11626, and 4,4',4''-Trimethoxytrityl chloride, L00629, respectively.
• For a one-pot procedure for the high yield, racemization-free N-tritylation of amino acids, by means of prior in situ O-silylation, see: J. Org. Chem., 47, 1324 (1982). N-Trt- derivatives of amino acids have also been converted to Leuchs' anhydrides by treatment with phosgene or triphosgene, and the products coupled with amino acid esters to give dipeptides in good yields without racemization: J. Org. Chem., 64, 2532 (1999). See also 9-Bromo-9-phenylfluorene, L14225.