均三甲苯-2-磺酰氯

• 产品号: A11775
• CAS号: 773-64-8
• 分子式: C9H11ClO2S
• 分子量: 218.70044
• 纯 度: 99%

产品别名

• 标题: Mesitylene-2-sulfonyl chloride
• IUPAC标准名: 2,4,6-trimethylbenzene-1-sulfonyl chloride
• IUPAC传统名: 2,4,6-trimethylbenzenesulfonyl chloride
• 别名: 2,4,6-Trimethylbenzenesulfonyl chloride

产品登记号

• EC号: 212-257-8
• Beilstein号: 1107601
• CAS号: 773-64-8
• MDL号: MFCD00007434

产品性质

• 纯度: 99%
• 沸点: 150°C/20mm
• 闪点: >110°C(230°F)
• 熔点: 53-57°C
• GHS危险声明: H314-H318
• 欧盟危险性物质标志: 腐蚀性(Corrosive) (C)
• GHS警示性声明: P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501A
• 危险公开号: 34
• RTECS编号: DB8930000
• 安全公开号: 26-36/37/39-45
• 保存注意事项: Moisture Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 8
• 联合国危险货物编号: UN3096
• 联合国危险货物包装类别(PG): II

参考文献

• For reviews of the use of hindered sulfonyl chlorides as condensing agents for the formation of the phosphate link of oligonucleotides, see: Angew. Chem. Int. Ed., 11, 451 (1972); Synthesis, 222 (1975); Chem. Rev., 77, 183 (1977). For reviews of oligonucleotide synthesis by the phosphotriester method, see: Heterocycles, 7, 1197 (1977); Tetrahedron, 34, 3143 (1978). Compare 2,4,6-Triisopropylbenzenesulfonyl chloride, A11458.
• Reagent for protection of the guanidino function of arginine residues as mesitylenesulfonyl (Mts) derivatives in peptide synthesis: J. Chem. Soc., Chem. Commun., 482 (1978); Chem. Pharm. Bull., 26, 3752 (1978); Int. J. Pept. Prot. Res., 14, 169 (1979). Deprotection can be effected with triflic acid in TFA in the presence of thioanisole as a cation scavenger: J. Chem. Soc., Chem. Commun., 1063 (1980).
• The indole nitrogen, e.g. in tryptophan residues, may also be protected as the Mts amide, stable to dilute alkali, hydrazine hydrate, TFA, 4N HCl in dioxane, or HBr in AcOH, but cleaved by MsOH, or TfOH in TFA: Chem. Pharm. Bull., 32, 2660 (1984). See Appendix 6.
• Selective reagent for sulfonylation of carbohydrates: J. Chem. Soc., Perkin 1, 1373 (1974).