2-(2-溴乙基)-1,3-二氧戊环烷

• 产品号: A11441
• CAS号: 18742-02-4
• 分子式: C5H9BrO2
• 分子量: 181.02776
• 纯 度: 95%, stab. with silver

产品别名

• 标题: 2-(2-Bromoethyl)-1,3-dioxolane
• IUPAC标准名: 2-(2-bromoethyl)-1,3-dioxolane
• IUPAC传统名: 2-(2-bromoethyl)-1,3-dioxolane
• 别名: 3-Bromopropionaldehyde ethylene acetal; 3-Bromopropanal 1,2-ethanediol acetal

产品登记号

• Beilstein号: 103516
• CAS号: 18742-02-4
• MDL号: MFCD00003216
• EC号: 242-551-1

产品性质

• 纯度: 95%, stab. with silver
• 沸点: 68-70°C/8mm
• 密度: 1.512
• 闪点: 65°C(149°F)
• 折射率: 1.4790
• GHS危险声明: H315-H319-H335-H227
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P210-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• 安全公开号: 26-37
• 保存注意事项: Light Sensitive
• TSCA收录: 否

参考文献

• For a review of 3-carbon homologating reagents, including many examples of Grignard and organocuprate reactions of these molecules, see: Chem. Rev., 84, 409 (1984).
• Masked ?-formylethyl synthon, compare preceding entry. The derived Grignard, which, unlike the dioxane analogue, is unstable above room temperature, shows similar attenuated reactivity in comparison with simple alkyl Grignard reagents, reacting with acid chlorides to give -ketoaldehydes without carbinol formation, and with enones to give, at low temperatures, predominantly the 1,4-addition product without the need for Cu catalysis:Tetrahedron Lett., 28, 3217 (1987).
• The Grignard undergoes coupling reactions (CuBr₂ + LiCl catalysis) with allylic halides: Tetrahedron Lett., 4549 (1979); J. Org. Chem., 46, 1504 (1981), allylic acetates: J. Am. Chem. Soc., 104, 2269 (1982), and primary alkyl bromides: J. Org. Chem., 48, 1767 (1983).