2,2'-二吡啶基 二硫醚

• 产品号: A11118
• CAS号: 2127-03-9
• 分子式: C10H8N2S2
• 分子量: 220.31392
• 纯 度: 98%

产品别名

• 标题: 2,2'-Dipyridyl disulfide
• IUPAC标准名: 2-(pyridin-2-yldisulfanyl)pyridine
• IUPAC传统名: 2,2'-dipyridyldisulfide
• 别名: 2,2'-Dithiodipyridine

产品登记号

• CAS号: 2127-03-9
• MDL号: MFCD00006287
• EC号: 218-343-1
• Beilstein号: 154629

产品性质

• 纯度: 98%
• 闪点: 210°C(410°F)
• 熔点: 56-59°C
• GHS危险声明: H315-H319-H335
• 欧盟危险性物质标志: 刺激性(Irritant) (Xi)
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 36/37/38
• 安全公开号: 26-37
• TSCA收录: 否

参考文献

• In combination with triphenylphosphine, acts as a peptide coupling reagent (see Appendix 6) in which water is removed by a mechanism whereby the phosphine is oxidized to the phosphine oxide and the disulfide reduced to the thiol: J. Am. Chem. Soc., 90, 4490 (1968); 91, 1554 (1969); Bull. Chem. Soc. Jpn., 43, 1271 (1970).
• The technique has also been widely applied for macrolactonization, via high-dilution cyclization of the 2-pyridine thioester: J. Am. Chem. Soc., 96, 5614 (1974); 97, 653, 654, 2287 (1975). The cyclization step can be catalyzed by silver ion: Helv. Chim. Acta, 57, 2661 (1974). See, e.g.: Org. Synth. Coll., 7, 470 (1990).
• In combination with tri-n-butylphosphine has been used for the activation of glycosides, e.g. in the formation of disaccarides: J. Am. Chem. Soc., 103, 4221 (1981); Tetrahedron, 47, 6435 (1991).