氯碘甲烷

• 产品号: A11032
• CAS号: 593-71-5
• 分子式: CH2ClI
• 分子量: 176.38405
• 纯 度: 98%, stab. with copper

产品别名

• 标题: Chloroiodomethane
• IUPAC标准名: chloro(iodo)methane
• IUPAC传统名: chloroiodomethane
• 别名: Methylene chloroiodide

产品登记号

• MDL号: MFCD00001078
• Beilstein号: 1730802
• CAS号: 593-71-5
• EC号: 209-804-8

产品性质

• 纯度: 98%, stab. with copper
• 沸点: 108-109°C
• 密度: 2.416
• 闪点: None
• 折射率: 1.5822
• GHS危险声明: H331-H302-H312-H315-H319-H335
• 欧盟危险性物质标志: X
• GHS警示性声明: P261-P305+P351+P338-P302+P352-P321-P405-P501A
• 危险公开号: 20/21/22-36/37/38
• 安全公开号: 23-26-36/37
• 保存注意事项: Light Sensitive
• TSCA收录: 否
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN2810
• 联合国危险货物包装类别(PG): III

参考文献

• The highly unstable ClCH₂Li, generated and trapped in situ: Tetrahedron Lett., 835 (1984); 795 (1986), converts esters to chloromethyl ketones: J. Chem. Soc., Chem. Commun., 969 (1994). Adducts with ketones can be further lithiated, enabling reaction with electrophiles on carbon: J. Chem. Soc., Perkin 1, 3339 (1988):
  
• In the absence of added electrophile, the dilithio-derivatives undergo elimination to give alkenes in good yield: J. Chem. Soc., Chem. Commun., 1665 (1986).
• Can be used in place of Diiodomethane, A15457, in the Simmons-Smith cyclopropanation reaction: Bull. Chem. Soc. Jpn., 46, 892, 1895 (1973); Synthesis, 700 (1977); J. Org. Chem., 56, 6974 (1991); J. Am. Chem. Soc., 114, 2592 (1992); Tetrahedron Lett.. 34, 7157 (1993). Preferred to CH₂I₂ in the methylenation of allylic alcohols, resulting in a more complete reaction: J. Org. Chem., 54, 3525 (1989).