苯并噻唑

• 产品号: A10380
• CAS号: 95-16-9
• 分子式: C7H5NS
• 分子量: 135.1863
• 纯 度: 97%

产品别名

• 标题: Benzothiazole
• IUPAC标准名: 1,3-benzothiazole
• IUPAC传统名: benzothiazole

产品登记号

• Beilstein号: 109468
• 默克索引号: 141107
• MDL号: MFCD00005775
• EC号: 202-396-2
• CAS号: 95-16-9

产品性质

• 纯度: 97%
• 沸点: 230°C
• 密度: 1.241
• 闪点: 107°C(224°F)
• 熔点: 2°C
• 折射率: 1.6420
• 溶解度: Slightly soluble in water. Soluble in alcohol, carbon disulfide
• GHS危险声明: H301-H311-H332-H319
• 欧盟危险性物质标志: X
• GHS警示性声明: P280H-P305+P351+P338-P309-P310
• 危险公开号: 20/21/22-36
• RTECS编号: DL0875000
• 安全公开号: 26-36/37
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN2810
• 联合国危险货物包装类别(PG): III

参考文献

• n-BuLi gives the 2-lithio-derivative, stable below -50^o, which behaves as a formyl anion equivalent, reacting with aldehydes and ketones. The derived alcohols have been transformed into various useful products, e.g. ɑ-hydroxy ketones: Tetrahedron Lett., 5, 9, 13, (1978); Bull. Chem. Soc. Jpn., 61, 3637 (1988):
  
• The lithio-derivative can also be acylated with esters, lactones, amides or nitriles. In these applications, benzothiazole is claimed to be superior to the better known 1,3-dithiane as a formyl anion synthon.
• See also 2-(Trimethylsilyl)benzothiazole, L11625, and 2-(Trimethylsilyl)thiazole, B21903.
• Reaction of the lithio-derivative at low temperatures with PCl₃ gives, as the major product, 2,2'-bibenzothiazole instead of the expected tertiary phosphine: Heterocycles, 30, 347 (1990). POCl₃ or SOCl₂ also promote the symmetrical coupling reaction: Heteroatom. Chem., 5, 409 (1994).