叠氮化钠

• 产品号: 14314
• CAS号: 26628-22-8
• 分子式: N3Na
• 分子量: 65.00987
• 纯 度: 99%

产品别名

• 标题: Sodium azide
• IUPAC标准名: sodium 2λ^5-triaz-1-en-2-yn-1-ide
• IUPAC传统名: sodium azide

产品登记号

• MDL号: MFCD00003536
• 默克索引号: 148581
• EC号: 247-852-1
• CAS号: 26628-22-8

产品性质

• 纯度: 99%
• 外观: Powder or Granular
• 密度: 1.846
• 熔点: ca 275°C dec
• 溶解度: Soluble in water and liquid ammonia. Slightly soluble in alcohol
• GHS危险声明: H300-H400-H410
• 欧盟危险性物质标志: 剧毒(Highly toxic) (T+)
• 欧盟危险性物质标志: 环境危害性(Nature polluting) (N)
• GHS警示性声明: P273-P264-P301+P310-P321-P405-P501A
• 危险公开号: 28-32-50/53
• RTECS编号: VY8050000
• 安全公开号: 28-45-60-61
• 保存注意事项: Air Sensitive
• TSCA收录: 是
• 联合国危险货物等级: 6.1
• 联合国危险货物编号: UN1687
• 联合国危险货物包装类别(PG): II

参考文献

• The reaction of alkyl halides with the highly-nucleophilic azide anion gives alkyl azides which, because of their facile reduction by hydrogenation, SnCl₂, P(III) reagents, etc., provide an excellent, mild route to primary amines. For a review of the preparation and synthetic uses of azides, see: Chem. Rev., 88, 297 (1988). The preparation of alkyl azides is ideally suited to phase-transfer methods: Synthesis, 823 (1979); Tetrahedron Lett., 3107 (1978); 30, 1245 (1989). The use of ultrasound has also been found to be effective: Acta Chem. Scand. B, 38, 895 (1984). For a one-pot conversion of alkyl bromides to amines using the Staudinger reaction, see Triethyl phosphite, L00339; see also Triphenylphosphine, L02502. For reviews, see: Tetrahedron, 37, 437 (1981); 48, 1353 (1992).
• Reaction with acyl halides or mixed anhydrides gives acyl azides. These undergo the Curtius rearrangement to isocyanates, which can be isolated, or hydrolyzed in situ to the primary amine. For examples, see: Org. Synth. Coll., 6, 95, 910 (1988).
• Reagent for selective cleavage of methyldiphenylsilyl ethers; see Diphenylmethylchlorosilane, L04162.
• For a brief feature on uses of this reagent in Organic synthesis, see: Synlett, 505 (2007).